姓名:明胜利
学科:基础兽医学
系别:动物生物技术系
电话/传真:
电子邮件:mingsl911102@163.com
通讯地址:郑州市郑东新区龙子湖高教园区15号 河南农业大学龙子湖校区第一实验楼QY千亿球友会网站 450046
简介
明胜利,男,中共党员,博士,讲师
研究领域
病毒与宿主相互作用。
学习及培养经历
2019年9月-2023年6月 河南农业大学 兽医学 博士研究生2016年9月-2019年6月 河南农业大学 基础兽医学 硕士研究生
2012年9月-2016年6月 河南农业大学 学士
工作经历
2024年1月-至今 河南农业大学
代表论著(*通讯作者)
1. Sheng-Li Ming#, Shuang Zhang#, Qi Wang#, Lei Zeng, Lu-Yu Zhou, Meng-Di Wang, Ying-Xian Ma, Li-Qiang Han, Kai Zhong, He-Shui Zhu, Yi-Lin Bai, Guo- Yu Yang, Jiang Wang*, Bei-Bei Chu*. Inhibition of USP14 influencesalphaherpesvirus proliferation by degrading viral VP16 protein via ER stress triggered selective autophagy. Autophagy. 2021;18(8):1801 1821.2. Sheng-Li Ming#, Lei Zeng#, Yu-Kun Guo, Shuang Zhang, Guo-Li Li, Ying-Xian Ma, Yun-Yun Zhai, Wen-Ru Chang, Le Yang, Jiang Wang, Guo-Yu Yang*, Bei-Bei Chu*.The human specific STING agonist G10 activates type I interferon and the NLRP3 inflammasome in porcine cells. Frontiers in Immunology. 2020;11:575818.
3. Bing-Qian Su#, Guo-Yu Yang, Jiang Wang*, Sheng-Li Ming*, Bei-Bei Chu*. Pseudorabies virus inhibits progesterone-induced inactivation of TRPML1 to facilitate viral entry. PLoS Pathogens. 2024;20(1): 0-e1011956.
4. Shuang Zhang#, Lei Zeng#, Bing-Qian Su, Guo-Yu Yang, Jiang Wang*, Sheng-Li Ming*, Bei-Bei Chu*. The glycoprotein 5 of porcine reproductive and respiratory syndrome virus stimulates mitochondrial ROS to facilitate viral replication. mBio, 2023;14(6): 0-e0265123.
5. Ying-Xian Ma#, Ya-Jing Chai#, Ya-Qi Han, Shi-Bo Zhao, Guo-Yu Yang, Jiang Wang*, Sheng-Li Ming*, Bei-Bei Chu*. Pseudorabies virus upregulates low-density lipoprotein receptors to facilitate viral entry. Journal of Virology. 2024;98(1): 0-e0166423.
6. Ying-Qian Han#, Sheng-Li Ming#, Hong-Tao Wu, Lei Zeng, Gen Ba, Jian Li, Wei-Fei Lu, Jie Han, Qia-Jun Du, Miao-Miao Sun, Guo-Yu Yang*, Jiang Wang*, Bei-Bei Chu*.Myostatin knockout induces apoptosis in human cervical cancer cells via elevated reactive oxygen species generation. Redox Biology. 2018 Oct; 9:412 428.
7. Lei Zeng#, Meng-Di Wang#, Sheng-Li Ming#, Guo-Li Li, Peng-Wei Yu, Yan-Li Qia, Da-Wei Jiang, Guo-Yu Yang*, Jiang Wang*, Bei-Bei Chu*. An effective inactivant based on singlet oxygen mediated lipid oxidation implicates a new paradigm for broad spectrum antivirals. Redox Biology. 2020 Sep;36:101601.
8. Jiang Wang#, Guo-Li Li#, Sheng-Li Ming#, Chun-Feng Wang, Li-Juan Shi1, Bing-Qian Su, Hong-Tao Wu, Lei Zeng, Ying-Qian Han, Zhong-Hu Liu, Da-Wei Jiang, Yong-Kun Du, Xiang-Dong Li, Gai-Ping Zhang, Guo-Yu Yang*, Bei-Bei Chu*. BRD4 inhibition exerts antiviral activity through DNA damage dependent innate immune responses. PLoS Pathogens. 2020 Mar; 16(3):e1008429.
9. Jiang Wang#, Chun-Feng Wang#, Sheng-Li Ming#, Guo-Li Li, Lei Zeng, Meng-Di Wang, Bing-Qian Su, Qi Wang, Guo-Yu Yang⁎, Bei-Bei Chu*.Porcine IFITM1 is a host restriction factor that inhibits pseudorabies virusinfection. International Journal of Biological Macromolecules. 2020 May;151.
10. Shuang Zhang#, Sheng-Li Ming#, Lei Zeng, Lu-Fang Wang, Chao Zhang, He-Shui Zhu, Guo-Yu Yang, Gai-Ping Zhang, Bei-Bei Chu, Jiang Wang. Alphaherpesvirus upregulates NDRG1 expression to facilitate the nuclear import of viral UL31 and UL34 proteins. Journal of Medical Virology. 2023 Feb
11. Yu-Kun Guo#, Sheng-Li Ming#, Lei Zeng, Wen-Ru Chang, Jia-Jia Pan,Chao Zhang, Bo Wan, Jiang Wang, Yu Su*, Guo-Yu Yang*, Bei-Bei Chu* .Inhibition of histone deacetylase 1 suppresses pseudorabies virus infection throughcGAS-STING antiviral innate immunity . Molecular Immunology. 2021 Aug.
寄语动医学子
不积跬步,无以至千里;不积小流,无以成江海。